The activity of CTO can be described as a process in which clinical trials (phase I, II, III, IV) are planned, executed, monitored and registered, reported and  archived upon external or internal request and this after  written approval of the (internal) Policy Committee CTO and the GZA  Ethics Committee. 
Data are systematically generated, documented and reported in accordance to the ICH Topic E6: guideline for Good Clinical Practice (GCP) and other applicable legislation as well as to the outlined study protocol.

External clients are commercial organisations, non-profit organisations or Clinical Research Organisations (CRO’s) on behalf of a commercial organisation. 
Internal clients are physicians of the Oncology Centre.  On a regular basis they initiate their own studies.